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May 2025

4 min read

The Mythical, Medicinal, and Cosmetic Power of Grapes

According to the Torah, Noah — said to have lived for 950 years — took cuttings from two plants onto his ark during the 120 years he spent preparing for the great flood: the vine and the fig tree. As one legend goes, after the waters receded and Noah began planting vineyards, the Devil appeared beside him and claimed ownership of the vines. In fact, versions of this story — told with different angels, plants, and ways of dividing the spoils — can be found in various traditions. In some, the archangel Gabriel intervenes and burns a portion of the cuttings; in others, the Devil agrees to take two-thirds of the harvest as his share.

If you’re ever boiling grape juice, tradition warns to make sure no more than one-third evaporates — otherwise, what remains might be considered the Devil’s portion. Interestingly, in some cultures, the alcohol that evaporates into the air is poetically referred to as “the angels’ share.”

It’s hardly surprising that grapes have long been caught in the tug of war between good and evil. From artistic depictions of mighty Roman emperors feasting on grapes to the story of Hamza Baba — a holy figure said to have harvested hundreds of kilos of grapes from a modest 5 to 10 square meter vineyard in defiance of Sultan Murad’s ban — grapes appear everywhere.

In Roman mythology, Bacchus, the god of wine, harvest, revelry, madness, and inspiration, finds his counterpart in the Greek god Dionysus. The great artist Michelangelo brought Bacchus to life in marble in 1496, portraying him with vine leaves in his hair, holding a bunch of grapes, with a panther lurking behind him. About a century later, the Italian painter Caravaggio also captured Bacchus in one of his works, filling the scene with grapes, vine leaves, and wine.

In Rumi’s Masnavi, the vine symbolizes spiritual transformation: the sour unripe grape represents immaturity, the ripened grape maturity, and wine signifies the burning away of the self.

In short, from prophetic traditions and Turkish legends to Greek mythology and countless folktales, grapes have woven themselves into nearly every chapter of human history.

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Grape seeds, a by-product of winemaking and juice production, hold untapped value of their own. Their oil can be extracted using traditional methods or organic solvents. However, cold pressing — a process free of heat and chemicals — preserves more of the oil’s beneficial compounds, making it a preferred method despite lower yields compared to chemical alternatives. This approach is also seen as safer and more appealing to consumers.

While often overshadowed by the fruit itself, grape seed oil has attracted considerable research interest. Numerous studies highlight its high antioxidant potential, health benefits, and possible protective effects against various cancer types in both humans and animals.

In a 2014 study conducted in China (1), grape seed oil was tested on mice. The results revealed that it delayed the destruction of pancreatic β-cells and positively influenced insulin secretion disrupted by high glucose levels — both significant findings.

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Another article published in 2024 (2) pointed out that grape seed oil is rich in antioxidants, vitamin E, phenolic compounds, and omega-6 fatty acids. The study suggested that it may help repair damage caused by free radicals and reduce the risk of heart disease. In its conclusion, the paper also noted the oil’s strong anti-inflammatory and antitumor potential due to its cytotoxic effects on tumor cells.

Could the authors of the 2024 study titled Ionic Liquid-Based Grapeseed Oil Emulsion for Enhanced Anti-Wrinkle Treatment (3) have drawn inspiration from those ancient works of art celebrating grapes? We’ll never know. But it’s now scientifically established that oils extracted from the seeds of those captivating grapes hold powerful effects in reducing wrinkles. The study focused on increasing the efficacy and dermal absorption of grape seed oil by combining it with ionic liquids and nanotechnology to create a specialized emulsion. The formulation was reported to enhance collagen content at low concentrations while reducing free radicals. To quote the conclusion directly:


“In clinical trials, it significantly increased the moisture content of the epidermal layer formed by cell-free skin surfaces; improved skin elasticity and firmness; reduced the degree of water loss through evaporation; and decreased both the number and length of facial wrinkles, including crow’s feet, under-eye wrinkles, nasolabial folds, and marionette lines.”

Disclaimer: The information we share about botanical products is derived from scientific studies examining their biochemical effects and is not intended as medical advice for the treatment of any condition. The findings of these studies do not provide guidance on how these botanical products should be used. Please remember that the most reliable way to safeguard your health is to consult health professionals who follow in the footsteps of Hippocrates.  
 
References

  1. Lai X, Kang X, Zeng L, Li J, Yang Y, Liu D. The protective effects and genetic pathways of thorn grape seeds oil against high glucose-induced apoptosis in pancreatic β-cells. BMC Complement Altern Med. 2014;14:10. 

  2. Nabavi, S. M., Marchese, A., Izadi, M., Curti, V., Daglia, M., & Nabavi, S. F. (2016). Grape seed oil: Health benefits and useful impacts on livestock performance and products quality – A review. Journal of the Science of Food and Agriculture, 96(13), 4270–4277.

  3. Li, X., Liu, T., Zhao, L., & Wang, X. (2024). Ionic liquid-based grapeseed oil emulsion for enhanced anti-wrinkle treatment. Journal of Cosmetic Dermatology, 23(1), 120–129.

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